Objectives: To determine the prevalence and clinical profile of peripheral arterial disease among chronic kidney disease patients undergoing hemodialysis using the ABI test at the Remedios Trinidad Romualdez Hospital.    Methods: We performed a prospective, cross - sectional analytical study involving eighty (80) adult CKD-HD patients with PAD from July 1, 2019 to July 31, 2020 at the Remedios Trinidad Romualdez Hospital, Tacloban City. Patients’ clinical characteristics and presence of risk factors such as smoking history, hypertension, diabetes, dyslipidemia, and atherosclerotic cardiovascular disease were reviewed. Laboratory parameters obtained were Fasting Blood Glucose, lipid profile and serum creatinine. Ankle – brachial index was measured using the American Heart Association 2005 guidelines. Descriptive statistics were utilized. Multivariate analysis was performed to compare the variables affecting the development of PAD while T – test was used to test for statistical significance. Results: The prevalence of PAD among CKD patients on hemodialysis was high at 31.25 %, majority of patients were more than 60 years of age at 71.25%, and predominantly males in 56 % of cases. Nine subjects, 36 % had normal BMI whereas 36 % were overweight among patients with PAD.  Hypertension, dyslipidemia and diabetes were the frequently associated comorbidities present in 92%, 64% and 52% of cases respectively.  Hypertension Stage 1 in 36% and stage 2 in 24% were observed. Dyslipidemia was a significant risk factor associated with PAD with a p value 0.02. Conclusions: The prevalence of PAD was 31.25% among patients with CKD on hemodialysis. Dyslipidemia posed a significant risk factor associated with PAD. Longitudinal research is recommended on routine use of ABI for screening of PAD among CKD patients and introducing medical and therapeutic intervention to improve patients’ outcomes.