Objectives: Cardiovascular disease is the leading cause of morbidity and death in kidney transplant recipients. This Study aims to examine the benefit of screening coronary computed tomographic angiography in kidney transplantation to prevent cardiovascular complications in long term. Methods:  Respective analysis was performed on 373 patients who underwent renal transplant between January 2011 and June 2015 at Severance Hospital of Yonsei University College of Medicine. Only patients with no history of coronary artery disease and with no signs or symptoms suggestive of cardiovascular disease during the past month were enrolled in the study. Study population was categorized into 2 groups; the intervention group that underwent coronary CT (n=86) and the control group that didn’t go through coronary CT (n=287). The primary outcome was a composite outcome of Major cardiovascular events or all-cause death. Results:  During 2,895 person-years (median, 8.4 years) of follow-up, the incidence rate of primary outcome was 31 (8.2%) in control group and 5 (5.8%) in intervention group, with corresponding incidence rates of 1.44 and 0.66 per 100 person-years, respectively. In multivariable-adjusted Cox model, screening coronary CT and intervention was associated with a 0.32-fold lower risk of the composite outcome (95% confidence interval [CI], 0.11- 0.92) compared with control group Conclusions: Early detection of CAD through coronary CT and with proper management combined, it leads to much lower incidence rate of composite cardiovascular outcome compared with the control group in long term.