Objectives: Measurements of kidney volume are important for the diagnosis, prognosis, and evaluation of the effects of drugs (tolvaptan)[오전1]  in autosomal dominant polycystic kidney disease (ADPKD). Non-contrast computed tomography (CT) is commonly used for volumetry, and this study demonstrated that low-dose CT can be used for volumetry as an alternative to standard-dose CT.   Methods: Axial images of standard-dose and low-dose CT with 1-mm slices were obtained from 24 ADPKD patients. The kidney volume was measured using Synapse 3D software through stereology. The volume measurements from both sets of images were compared using R2, Bland-Altman plots, and intra-class correlation coefficient (ICC) s. Results: Patients’ mean age was 48.4±10.9 years, and 45.8% (n=11) were men. The mean total kidney volume on standard-dose CT was 1501±838.2 mL. The R2 of volume using standard-dose and low-dose CT was 0.995. In the Bland-Altman plot, except for one large volume, the two measurements were consistent, and the ICC was also high (0.998). The CT radiation dose (dose-length product, mGy·cm) from standard-dose CT was 229±68, and that of low-dose CT was 50±19. Comparable volumes were obtained using low-dose CT, with a dose reduction of about 20% relative to standard-dose CT. Conclusions: Standard-dose and low-dose CT showed comparable kidney volume results in ADPKD patients. Therefore, low-dose CT can be used to minimize radiation exposure in ADPKD volumetry.