- Sarcopenia, nutritional status and mortality risk assessed using bioimpedance spectroscopy in the elderly living in long-term care facility
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Hyokyeong Yu,Song In Baeg,Hye Min Choi,Dong-Jin Oh,Young Eun Kwon
2022 ; 2022(1):
- 논문분류 :
- 춘계학술대회 초록집
Objectives: This study was aimed to clarify the impact of sarcopenia and phase angle (PA) on mortality risks.
Methods: This prospective cohort study enrolled the elderly residents who were living in nine long-term care facilities. We collected participants’ data such as body mass index (BMI), comorbidities, and laboratory data from September to October in 2017 and mortality data until October 2019. Nutritional status was evaluated using mini nutritional assessment (MNA) score and multi-frequency bioimpedance spectroscopy was used to check body composition including PA. Appendicular skeletal muscle mass was calculated using the equation according to the article of Lin T-Y et al (Clinical Nutrition, 40(5), 3288-3295, 2021). Sarcopenia was diagnosed by European Working Group on Sarcopenia in Older People (EWGSOP2) definition (sarcopenia vs. normal group). Moreover, we divided the participants into two groups according to the median PA values 3.65̊ (high vs. low group). In addition to the comparison between the two groups, and multivariate regression analyses were performed to verify the association with mortality risks according to sarcopenia diagnosis or phase angle group.
Results: A total number of 279 elderly participants were enrolled, and 238 seniors were diagnosed with sarcopenia according to the EWGSOP2 guideline. Median age was 83 years old and median BMI was 20.4 kg/m2. Sarcopenia group were older than normal group, showed lower BMI and had lower MNA score. Sarcopenia was associated with higher mortality risk after adjusting age, gender and diabetes mellitus. Low phase angle was associated with sarcopenia, age, female gender, lower MNA score and overhydrated volume. In addition, low phase angle group was a significant predictor of mortality after adjusting age, gender, diabetes mellitus and MNA score.
Conclusions: Sarcopenia was very prevalent in the elderly of long-term facility care. Sarcopenia and low phase angle group were significantly associated with higher mortality risks.