Elevation in blood pressure (BP) is associated with an increased risk of adverse outcomes in chronic kidney disease (CKD). Progressive loss of kidney function leads to a rise in BP via sympathetic nervous system overactivity, the renin-angiotensin-aldosterone system (RAAS), and sodium retention. Thus, BP management is an important component among the routine clinical practice for CKD patient to prevent in the CKD progression and cardiovascular mortality.  BP reading at a single time point does not sufficiently capture the entire risk profile given that BP is a dynamic physiological parameter rather than static in response to various factors such as changes in pharmacologic agents, sodium retention, and RAAS activation. In support of this concept, most previous studies have focused primarily on long-term cardiovascular disease outcomes related to longitudinal BP variability trends. However, the less attention was given to relationship between the BP and CKD outcomes. There is mounting evidence regarding the temporal BP trajectories and long-term CKD progression.  In this lecture, the results of recent studies on the relationship between longitudinal BP trajectories and kidney outcomes will be discussed.