Both adequate uremic toxin removal and volume control are essential in peritoneal dialysis (PD) to improve patient outcome. However, parameters of urea kinetic such as Kt/V has been questioned. On the other hand, fluid overload is presumed to be associated with cardiovascular risk and be more important in patient survival. Recent data reported PD patients showed better survival than facility hemodialysis patients. Particularly, automated PD demonstrated to have a benefit to remove fluid overload. Fluid overload was more expressed in PD compared with HD. The prevalence of fluid overload in PD was associated with higher age, male gender, diabetes, and lower body mass index. To manage volume control in PD patients, dietary salt/water restriction, blood glucose control, residual renal function, adherence to the PD prescription are important. Icodextran use also are useful in removal of fluid overload. To date, remote monitoring of APD could be helpful to report fluid overload as events occur. The bioimpedance analysis (BIA) has been better to evaluate fluid overload, but not measure the intravascular effective volume. The BIA use did not have a benefit of the survival in PD patients. Although the most efforts leading to a failure of volume control, PD should be transited into hemodialysis timely.