Objectives: Obstructive sleep apnea (OSA) is associated with an increased risk of numerous metabolic complications, including cardiovascular diseases, and its prevalence is increasing worldwide. The present study examined the clinical characteristics and comorbidities of OSA among Korean adults with albuminuria and aimed to demonstrate the association with OSA. Methods: We screened subjects aged ≥40 who underwent the Korean National Health and Nutrition Examination survey (2019-2021) and included those who completed the STOP-BANG questionnaire and underwent urine albumin quantification. The STOP-BANG questionnaire, a screening tool for OSA, was used to determine the severity of the risk of OSA. The association of albuminuria and the clinical parameters, including OSA, was examined with multiple logistic regression analysis. Results: Among a total of 22,559 subjects, 10,923 were acceptable for the study. Subjects with albuminuria showed a higher STOP-BANG score compared to subjects without albuminuria. Albuminuria was significantly associated with a high STOP-BANG score (odds ratio [OR], 2.01; 95% confidence interval [CI], 1.66 to 2.43), and the result was consistent after multivariate adjusted analysis. Moreover, the association was more prominent with subjects with an increased amount of albuminuria. Inversely, a high STOP-BANG score also showed an association with albuminuria (OR 2.51; 95% CI 1.89 to 3.31). Conclusions: In the present study, albuminuria showed a significant association with a high risk of OSA, as inferred from the high STOP-BANG score. Among the subjects with albuminuria, screening, and monitoring for OSA may be beneficial in minimizing future metabolic complications.