Objectives: In patients with CKD, there are more studies on cf-PWV and mortality, but fewer studies on cr-PWV and cd-PWV. This study aims at examining the relationship between cf-PWV, cr-PWV, and cd-PWV and mortality in patients with CKD. Methods: This was a single-center cohort study. CKD patients with eGFR <60 ml/min/1.73 m2 were recruited. Their baseline cf-PWV, cr-PWV, and cd-PWV were collected, and then were followed up for the occurrence of all-cause and cardiovascular (CV) death. Cox proportional hazards model were used to examine the association of cf-PWV, cr-PWV, and cd-PWV with mortality. Time-dependent receiver operating characteristic (ROC) curve was used to evaluate the predicting performance of cf-PWV on CV mortality. Results: A total of 233 patients were enrolled. Their average cf-PWV, cr-PWV, and cd-PWV were 12.8±3.6 m/s, 9.9±2.0 m/s, and 9.4±3.7 m/s, respectively. During 9.0(4.0, 12.6) years of follow-up, 144 (61.8%) patients died, of which 76 (52.8%) were due to CV death. In the univariate Cox regression analysis, cf-PWV was associated with all-cause mortality; both cf-PWV and cr-PWV were associated with CV mortality. After adjustment for confounding factors, only cf-PWV was an independent risk factor for CV mortality [HR 1.198, 95% CI (1.097, 1.308)]. The areas under the curve (AUC) of cf-PWV for 1-, 3-, 5-, and 10-year of CV death were 0.78, 0.76, 0.70, and 0.75, respectively. Conclusions: In CKD patients, cf-PWV is associated with CV mortality, and the predictive vitality remains significant even after 10 years. Cr-PWV and cd-PWV are not associated with either all-cause or CV mortality, therefore, routine monitoring of these parameters is not needed.