Renal biopsy is an essential procedure for diagnosis and prognosis of the glomerular diseases, however it needs a lot of skill and experience to do and usually requires admission for a couple of days, unless sometimes needs an embolization, transfusion, nephrectomy etc. We have an experience of more than 3,000 cases of renal biopsy without major complications such as bleeding, embolization, nephrectomy etc. however all patients were admitted for a couple of days. Recently we performed 2,000 cases of renal biopsies at the OPD level without complications since last 11 years. Before renal biopsy we checked bleeding tendencies. Blood thinning agents were discontinued for more than 1 week. Anesthesia were done by local by lidocaine but sometimes used IV ketamine for young children who are uncooperative. Disposable kidney biopsy needle (TSK lab) were inserted under the ultrasound guide (LOGIQ 10S). We checked perirenal hematoma, AV fisutula etc every one hour for 4 to 6 hours until discharge. During last 11 years. we performed 2,000 cases of renal biopsies at OPD level without admission. Pathology reading was done by renal pathology specialist. All renal biopsies were done at OPD level without admission. Three patients were developed hematomas measuring 5 cm but there were no AV fistula and uncontrollable bleedings. Biopsy results were as follows: IgA nephropathy 669(33.45%), MesPGN 326 (16.3%), FSGS 269 (13.45%), Focal nonspecific glomerulonephritis 207 (10.35%), Diabetic kidney disease 85 (4.25%), Tubulointerstitial nephritis 88 (4.4%), Podocyte disease 52 (2.6%), Allergic purpura nephritis 52 (2.6%), Minor change 52 (2.6%), Membranous nephropathy 50 (2.5%), Obesity related glomerulopathy 26 (1.3%), ESRD 22 (1.1%), Alport syndrome 16 (0.8%), Membranoproliferative glomerulonephritis 14 ( 0.7%), Lupus nephritis 12 (0.6%), C1q nephropathy 9 (0.45%), Others 51 (2.55%). OPD level renal biopsy might be a safe procedure if done properly