Septic acute kidney injury(AKI) is common in hospitalized patients and has a poor prognosis. Therefore, early diagnosis and appropriate treatment of sepsis should be needed, and the prognosis should be improved by reducing the occurrence of acute kidney injury by infection. We aim to investigate the association of septic AKI with clinical outcomes.   We retrospectively evaluated the medical records of patients who were diagnosed with septic AKI from January 2011 to December 2016 in our institution. We compared laboratory finding between patient’s baseline and at the time of hospitalization to assess AKI. We divided groups into AKI group and nonAKI group. The primary endpoints was all cause mortality, and secondary endpoints were prognostic factors and outcomes associated with AKI. Stastical analysis was perfomed through propensity score matching method.   A total of 1644 patients were evaluated, 1:4 matching was evaluated in AKI group(n=244) and nonAKI group(n=976). A mean age was 72.82±11.51 years old and incidence of AKI was 2.9%. Only 0.9% of patients without septic AKI died at the time of hospitalization, whereas AKI group had a statistically higher mortality rate (0.9% vs 10.7%, p<0.001) In the AKI group, the SOFA score(3.56±2.12 vs 1.34±1.40, p<0.001) and SIRS(35.7% vs 10.1%, p<0.001) were higher than the non-AKI group, and length of hospital stay was significantly longer(10.7±8.5 vs 14.9±11.3, p<0.001). As a prognostic factor for all cause mortality, BUN/albumin ratio was significantly higher in AKI group.(14.3±10.4 vs 5.1±4.2, p<0.001)   Acute kidney injury can be accompanied by sepsiswhich leads to poor prognosis. All cause of death increases due to AKI, and prognosis can be assessed through SOFA score and blood urea nitrogen to albumin ratio.